Measuring Gene Expression

Author: Matthew Avison
Publisher: Taylor & Francis
ISBN: 9781134189175
Release Date: 2008-04-18
Genre: Science

In the post-genomic age, much biomedical research looks at when, where, and at what level genes are expressed. Measuring Gene Expression is an all-in-one introduction to the main methods of measuring gene expression, including RT-PCR, differential display, RNA interference, reporter genes, microarrays, and proteomics, as well as a section on RNA isolation and analysis. There is an overview of each method: its pros and cons, sample preparation, sources of error, and data interpretation.

Principles and Techniques of Biochemistry and Molecular Biology

Author: Keith Wilson
Publisher: Cambridge University Press
ISBN: 9781107393493
Release Date: 2010-03-04
Genre: Science

This best-selling undergraduate textbook provides an introduction to key experimental techniques from across the biosciences. It uniquely integrates the theories and practices that drive the fields of biology and medicine, comprehensively covering both the methods students will encounter in lab classes and those that underpin recent advances and discoveries. Its problem-solving approach continues with worked examples that set a challenge and then show students how the challenge is met. New to this edition are case studies, for example, that illustrate the relevance of the principles and techniques to the diagnosis and treatment of individual patients. Coverage is expanded to include a section on stem cells, chapters on immunochemical techniques and spectroscopy techniques, and additional chapters on drug discovery and development, and clinical biochemistry. Experimental design and the statistical analysis of data are emphasised throughout to ensure students are equipped to successfully plan their own experiments and examine the results obtained.

Microarrays Microplates

Author: Shu Ye
Publisher: Garland Science
ISBN: 185996074X
Release Date: 2003
Genre: Medical

The 'Advanced Methods' series is intended for advanced undergraduates, postgraduates and established research scientists. Titles in the series are designed to cover current important areas of research in life sciences, and include both theoretical background and detailed protocols. The aim is to give researchers sufficient theory, supported by references, to take the given protocols and adapt them to their particular experimental systems. Microarrays and Microplates title looks at the new microarray and microplate-based technologies which facilitate large-scale analysis of DNA sequence variants, mRNA molecules and proteins. The book provides a review of the various methodologies being used to identify genetic variants and gene regulation and guides readers through both the application of these methodologies and experimental procedures.

The Oxford Handbook of Psychoneuroimmunology

Author: Suzanne Segerstrom
Publisher: Oxford University Press
ISBN: 9780195394399
Release Date: 2012-07-19
Genre: Medical

This volume collects the state-of-the-art applications of psychological theory to the interactions among the mind, the nervous system, and the immune system, including applications drawn from affective science, developmental psychology, behavioral neuroscience, and clinical psychology.

Wilson and Walker s Principles and Techniques of Biochemistry and Molecular Biology

Author: Andreas Hofmann
Publisher: Cambridge University Press
ISBN: 9781108365253
Release Date: 2018-04-19
Genre: Science

Bringing this best-selling textbook right up to date, the new edition uniquely integrates the theories and methods that drive the fields of biology, biotechnology and medicine, comprehensively covering both the techniques students will encounter in lab classes and those that underpin current key advances and discoveries. The contents have been updated to include both traditional and cutting-edge techniques most commonly used in current life science research. Emphasis is placed on understanding the theory behind the techniques, as well as analysis of the resulting data. New chapters cover proteomics, genomics, metabolomics, bioinformatics, as well as data analysis and visualisation. Using accessible language to describe concepts and methods, and with a wealth of new in-text worked examples to challenge students' understanding, this textbook provides an essential guide to the key techniques used in current bioscience research.

Gentechnologie f r Einsteiger

Author: Terence A. Brown
Publisher: Springer
ISBN: 3827413028
Release Date: 2002
Genre:

T. A. Browns "Gentechnologie fA1/4r Einsteiger" hat sich in mehreren Auflagen international als StandardeinfA1/4hrung in die Genklonierung und DNA-Analyse etabliert. Das Grundlagenlehrbuch setzt nur wenig Kenntnisse in Molekularbiologie und Genetik voraus und erlAutert in klarer Sprache sowohl die fundamentalen Prinzipien der wichtigsten gentechnologischen Methoden als auch die immer breiter werdende Palette ihrer Anwendungen. Die groAe Bedeutung der Gentechnologie fA1/4r die Grundlagenforschung und fA1/4r neue Entwicklungen in Biotechnologie und Medizin wird klar herausgearbeitet. Aoeber 250 zweifarbige Illustrationen erleichtern das VerstAndnis des Stoffes und machen die Konzepte und Arbeitstechniken der Gentechnologen anschaulich. Die neue Auflage ist vollstAndig A1/4berarbeitet und enthAlt zwei neue Kapitel. Eines prAsentiert die Methoden, mit denen man ganze Genome sequenziert, und beschreibt, was man aus den gewonnenen Sequenzinformationen ablesen kann. Das zweite widmet sich den Anwendungen der Gentechnologie in der Gerichtsmedizin - ein spannendes und aufschlussreiches Beispiel des Einsatzpotenzials der DNA-Analyse. Der groAen Bedeutung der Polymerasekettenreaktion (PCR) entsprechend wird diese Technik jetzt in einem frA1/4hen Abschnitt des Buches behandelt und durchgehend stArker berA1/4cksichtigt.

Biology of Aging

Author: Roger B. McDonald
Publisher: Garland Science
ISBN: 9781317970828
Release Date: 2013-07-02
Genre: Science

Biology of Aging presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material.

Molecular Microbial Ecology

Author: A. Mark Osborn
Publisher: Garland Science
ISBN: 1859962831
Release Date: 2005
Genre: Science

Microoganisms are distributed across every ecosystem, and microbial transformations are fundamental to the operation of the biosphere. Microbial ecology is the study of this interaction between microorganisms and their environment, and arguably represents one of the most important areas of biological research. Yet for many years our study of microbial flora was severely limited: the primary method of culturing microorganisms on media allowed us to study only between 0.1 and 10% of the total microbial flora in any given environment. Molecular Microbial Ecology gives a comprehensive guide to the recent revolution in the study of microorganisms in the environment. Details are given on molecular methods for isolating some of the previously uncultured and numerically dominant microbial groups. PCR-based approaches to studying prokaryotic systematics are described, including ribosomal RNA analysis and stable isotope probing. Later chapters cover DNA hybridisation techniques (including fluorescent in situ hybridisation), as well as genomic and metagenomic approaches to microbial ecology. Gathering together some of the world's leading experts, this book provides an invaluable introduction to the modern theory and molecular methods used in studying microbial ecology.

Molekularbiologie der Zelle

Author: Bruce Alberts
Publisher: John Wiley & Sons
ISBN: 9783527323845
Release Date: 2011
Genre: Cells

Seit einem Vierteljahrhundert ist 'Molekularbiologie der Zelle' das führende Lehrbuch im Bereich Zellbiologie. Diese erfolgreiche Tradition wird nun mit der fünften Auflage fortgesetzt, die vollständig überarbeitet und aktualisiert wurde. Mit zahlreichen inhaltlichen Neuerungen stellt sie unser aktuelles, sich rasch weiterentwickelndes Wissens zum zentralen Gegenstand der Biologie dar - der Zelle.

Textbook of Medical Physiology

Author: Arthur C. Guyton
Publisher: Saunders
ISBN: UCSD:31822035703149
Release Date: 2006
Genre: Human physiology

This new edition contains concise revised information covering all the areas of medical physiology. Chapters include the heart, respiration, the nervous system, neurophysiology and sports physiology.

Understanding Bioinformatics

Author: Marketa J. Zvelebil
Publisher: Garland Science
ISBN: 0815340249
Release Date: 2008
Genre: Medical

Suitable for advanced undergraduates & postgraduates, this book provides a definitive guide to bioinformatics. It takes a conceptual approach & guides the reader from first principles through to an understanding of the computational techniques & the key algorithms.